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Rantudil Forte 60 Mg 20 Capsule

Acemetacin (Rantudil)
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Information specific to: Acemetacin (Rantudil)60mg capsules when used in Osteoarthritis.

Acemetacin (Rantudil)(Assem-etta-sin) is a medicine which is used in rheumatoid arthritis, osteoarthritis, treatment of low back pain and relieving post-operative pain.

The information in this Medicine Guide for Acemetacin (Rantudil)varies according to the condition being treated and the particular preparation used.

Your medicine

Acemetacin (Rantudil) helps to reduce inflammation and to reduce pain. Acemetacin (Rantudil) works by blocking the production of some of the body chemicals that cause inflammation, pain, stiffness, tenderness, swelling and increased temperature.

By reducing inflammation in conditions affecting muscles and jointsAcemetacin (Rantudil) helps to improve movement.

Acemetacin (Rantudil) can take a few weeks to help improve inflammation but can start to relieve pain after the first few doses.

Other information about Acemetacin (Rantudil):

  • this medicine will normally be prescribed at the lowest possible dose for the shortest time to reduce the chance of side-effects

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Whether this medicine (Rantudil) is suitable for you

Acemetacin (Rantudil)is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

  • are a female having difficulty with conceiving or are having investigations for infertility
  • are a female who is trying to have a baby
  • are allergic or sensitive to or have had a bad reaction to indometacin, ibuprofen, aspirin or other NSAIDs in the past
  • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
  • are elderly
  • are pregnant
  • have an autoimmune problem
  • have an infection
  • have angioneurotic oedema
  • have cerebrovascular problems
  • have circulation problems
  • have connective tissue problems
  • have epilepsy
  • have had a gastrointestinal bleeding or perforation after taking NSAIDs
  • have had mifepristone within the last 8-12 days
  • have kidney problems
  • have liver problems
  • have lupus or a lupus-like problem
  • have nasal polyps
  • have or have had asthma
  • have or have had Crohn's disease
  • have or have had gastrointestinal problems such as peptic ulcers or bleeding
  • have or have had heart problems
  • have or have had high blood pressure
  • have or have had ulcerative colitis
  • have Parkinson's disease or Parkinson-like symptoms
  • have psychiatric problems
  • have risk factors for heart or circulation problems such as: diabetes, hyperlipidaemia or smoking

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child or an adolescent.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

  • to check that this medicine is not having any undesired effects

Over time it is possible that Acemetacin (Rantudil) can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Acemetacin (Rantudil)has become unsuitable, it is important that the prescriber is contacted immediately.


Alcohol can interact with certain medicines.

In the case of Acemetacin (Rantudil):

  • there are no known interactions between alcohol and Acemetacin (Rantudil)


Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Acemetacin (Rantudil):

  • there are no specific foods that you must exclude from your diet when taking Acemetacin

Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Acemetacin (Rantudil):

  • this medicine could affect your ability to drive or operate machinery

You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Acemetacin (Rantudil):

  • the use of this medicine during pregnancy is not recommended. You should only take this medicine during pregnancy if your doctor thinks that you need it
  • this medicine may decrease female fertility. This medicine is not recommended for women who are trying to conceive
  • this medicine may lengthen or delay labour
  • if you take this medicine during your pregnancy, your baby may have some problems after birth

You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.

If the decision is that you should not have Acemetacin, then you should discuss whether there is an alternative medicine that you could take during pregnancy.


Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Acemetacin (Rantudil):

  • you should only take this medicine while breast-feeding if your doctor thinks you need it

Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. You should only breast-feed your baby while taking this medicine on the advice of your doctor or midwife.

Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Acemetacin (Rantudil):

  • aspirin
  • ciclosporin
  • diflunisal
  • haloperidol
  • lithium
  • methotrexate
  • mifepristone
  • probenecid
  • tacrolimus
  • warfarin
  • zidovudine

The following types of medicine may interact with Acemetacin (Rantudil):

  • anticoagulants
  • antihypertensives
  • antiplatelets
  • antipsychotics
  • cardiac glycosides
  • corticosteroids
  • COX-2 inhibitors
  • diuretics
  • medicines that cause gastrointestinal problems or bleeding
  • other non-steroidal anti-inflammatories
  • potassium sparing diuretics
  • quinolones
  • salicylates
  • selective serotonin re-uptake inhibitors

If you are taking Acemetacin (Rantudil) and one of the above medicines or types of medicines, make sure your prescriber knows about it.

Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Acemetacin.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

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