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Alphagan-P %0,15 5 Ml

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Brimonidine Ophthalmic

pronounced as(bri moe' ni deen)

Why is this medication prescribed?How should this medicine be used?Other uses for this medicineWhat special precautions should I follow?What should I do if I forget a dose?What side effects can this medication cause?

What should I know about storage and disposal of this medication?In case of emergency/overdoseWhat other information should I know?Brand namesBrand names of combination products

Why is this medication prescribed?

Ophthalmic brimonidine is used to lower pressure in the eyes in patients who have glaucoma (high pressure in the eyes that may damage nerves and cause vision loss) and ocular hypertension (pressure in the eyes that is higher than normal but not high enough to cause vision loss). Brimonidine is in a class of drugs called alpha adrenergic agonists. Brimonidine works by decreasing the amount of fluid in the eyes.

How should this medicine be used?

Ophthalmic brimonidine comes as a solution (liquid) to instill in the eyes. It is usually instilled in the affected eye(s) three times a day. Use brimonidine eye drops at around the same times every day, and try to space your 3 daily doses about 8 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use brimonidine eye drops exactly as directed. Do not use more or less of them or use them more often than prescribed by your doctor.

Brimonidine eye drops may control your condition, but will not cure it. Continue to use brimonidine eye drops even if you feel well. Do not stop using brimonidine eye drops without talking to your doctor.

To instill the eye drops, follow these steps:

  1. Wash your hands thoroughly with soap and water.
  2. Check the dropper tip to make sure that it is not      chipped or cracked.
  3. Avoid touching the dropper tip against your eye      or anything else; eye drops and droppers must be kept clean.
  4. While tilting your head back, pull down the lower      lid of your eye with your index finger to form a pocket.
  5. Hold the dropper (tip down) with the other hand,      as close to the eye as possible without touching it.
  6. Brace the remaining fingers of that hand against      your face.
  7. While looking up, gently squeeze the dropper so      that a single drop falls into the pocket made by the lower eyelid. Remove      your index finger from the lower eyelid.
  8. Close your eye for 2 to 3 minutes and tip your      head down as though looking at the floor. Try not to blink or squeeze your      eyelids.
  9. Place a finger on the tear duct and apply gentle      pressure.
  10. Wipe any excess liquid from your face with a      tissue.
  11. If you are to use more than one drop in the same      eye, wait at least 5 minutes before instilling the next drop.
  12. Replace and tighten the cap on the dropper      bottle. Do not wipe or rinse the dropper tip.
  13. Wash your hands to remove any medication.

Other uses for this medicine


This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?


Before using brimonidine eye drops,

  • tell your doctor      or pharmacist if you are allergic to brimonidine eye drops or any other      medications.
  • do not use      brimonidine eye drops if you are taking a monoamine oxidase (MAO)      inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline      (Eldepryl), or tranylcypromine (Parnate).
  • tell your doctor      and pharmacist what prescription and nonprescription medications,      vitamins, nutritional supplements, and herbal products you are taking or      plan to take. Be sure to mention any of the following: antidepressants      such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine      (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan),      imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline      (Vivactil), and trimipramine (Surmontil); barbiturates such as      phenobarbital and secobarbital (Seconal); digoxin (Lanoxin); medications      for anxiety, high blood pressure, mental illness, pain, or seizures;      sedatives; sleeping pills; and tranquilizers. Your doctor may need to      change the doses of your medications or monitor you carefully for side      effects.
  • if you are using      any other topical eye medications, instill them 5 minutes before or 5      minutes after you instill brimonidine eye drops.
  • tell your doctor      if you often feel dizzy when you sit or stand from a lying position and if      you have or have ever had depression; conditions that affect your blood      circulation including Raynaud's disease (a condition that causes attacks      of low blood circulation to the fingers and toes), thromboangiitis      obliterans (a condition that causes poor blood circulation in the hands      and feet), and problems with blood flow to your heart or brain; or heart,      kidney, or liver disease.
  • tell your doctor      if you are pregnant or plan to become pregnant. If you become pregnant      while you are using brimonidine eye drops, call your doctor. Do not      breast-feed while you are using brimonidine eye drops.
  • if you are      having surgery, including dental surgery, tell your doctor or dentist that      you are using brimonidine eye drops.
  • you should know      that brimonidine eye drops may make you drowsy. Your vision may be blurry      for a few minutes after you instill the eye drops. Do not drive a car or      operate machinery until you know how this medication affects you.
  • ask your doctor      about the safe use of alcohol while you are using brimonidine eye drops.      Alcohol can make the drowsiness caused by brimonidine eye drops worse.
  • tell your doctor      if you wear soft contact lenses. Remove your soft contact lenses before      instilling brimonidine eye drops and wait at least 15 minutes after using      the medication to replace your lenses.

What should I do if I forget a dose?


Instill the missed dose as soon as you remember it. However, if is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.

What side effects can this medication cause?


Brimonidine eye drops may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • itchy, irritated, red, stinging, or burning eyes
  • dry eyes
  • watery or runny eyes
  • red or swollen eyelids
  • sensitivity to light
  • blurred vision
  • headache
  • drowsiness
  • difficulty falling asleep or staying asleep
  • dry mouth
  • runny nose and other cold symptoms
  • cough
  • sore throat
  • flu-like symptoms
  • pain or pressure in the face
  • heartburn

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

  • rash
  • difficulty breathing
  • seeing specks or flashes of light
  • blind spots
  • fainting
  • dizziness
  • nausea

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].

What should I know about storage and disposal of this medication?


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose


In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?


Keep all appointments with your doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names


  • Alphagan P®

Brand names of combination products


  • Combigan® (containing Brimonidine, Timolol)

Last Revised - 01/01/2011


Please e-mail us, that you can’t find brand or generic drugs on our site or the other online drug store.

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