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Breast Cancer

Breast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gland. The molecular subtypes of breast cancer, which are based on the presence or absence of hormone receptors (estrogen and progesterone subtypes) and human epidermal growth factor receptor-2 (HER2), include: hormone receptor positive and HER2 negative (luminal A subtype), hormone receptor positive and HER2 positive (luminal B subtype), hormone receptor negative and HER2 positive (HER2 positive), and hormone receptor negative and HER2 negative (basal-like or triple-negative breast cancers (TNBCs)). Hormone receptor positive breast cancers are largely driven by the estrogen/ER pathway. In HER2 positive breast tumours, HER2 activates the PI3K/AKT and the RAS/RAF/MAPK pathways, and stimulate cell growth, survival and differentiation. In patients suffering from TNBC, the deregulation of various signalling pathways (Notch and Wnt/beta-catenin), EGFR protein have been confirmed. In the case of breast cancer only 8% of all cancers are hereditary, a phenomenon linked to genetic changes in BRCA1 or BRCA2. Somatic mutations in only three genes (TP53, PIK3CA and GATA3) occurred at >10% incidence across all breast cancers.

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Adrimisin (Doxorubicin (Adriamycin)) 10 mg 1 Vial Please Ask Availability
Adrimisin (Doxorubicin (Adriamycin)) 50 mg 1 Vial Please Ask Availability
Anzatax (Paclitaxel) 100 mg/16.7 ml 1x16.7 ml Vial Please Ask Availability

Anzatax (Paclitaxel) 100 mg/16.7 ml 1x16.7 ml Vial

Anzatax (Paclitaxel) 100 mg/16.7 ml 1x16.7 ml Vial..

$149.00

Anzatax (Paclitaxel) 30 mg/5 ml 1x5 ml Vial Please Ask Availability
Anzatax (Paclitaxel) 300 mg/50 ml 1x50 ml Vial Please Ask Availability
Anzatax (Paclitaxel) 50 mg/25 ml 1x25 ml Vial Please Ask Availability

Aromasin 25 Mg 30 Tablets

FULL PRESCRIBING INFORMATION: CONTENTS* 1 INDICATIONS AND USAGE 1.1 Adjuvant Tr..

$39.00

Ataxil (Paclitaxel) 100 mg/16.7 ml 1x16.7 ml Vial Please Ask Availability
Ataxil (Paclitaxel) 30 mg/5 ml 1x5 ml Vial Please Ask Availability
Ataxil (Paclitaxel) 300 mg/50 ml 1x50 ml Vial Please Ask Availability
Caelyx (Doxorubicin (Adriamycin)) 0 mg/10 ml 1x10 ml Vial Please Ask Availability

Caelyx (Doxorubicin (Adriamycin)) 0 mg/10 ml 1x10 ml Vial

Caelyx (Doxorubicin (Adriamycin)) 0 mg/10 ml 1x10 ml Vial..

$421.00

Capetabin (Capecitabine) 500 mg 120 Film-Coated Tablets Please Ask Availability

Capetabin (Capecitabine) 500 mg 120 Film-Coated Tablets

Capetabin (Capecitabine) 500 mg 120 Film-Coated Tablets..

$125.00

Docexus (Docetaxel) 20 mg/0.5 ml 1 Vial Please Ask Availability
Docexus (Docetaxel) 80 mg/2 ml 1 Vial Please Ask Availability